Every drug you put into your body passes through your kidneys. If the drug is not taken following your healthcare provider’s instructions, or if it is an illegal substance, it can cause injury to the kidneys.
Below are the top ten prescription drugs that may damage the kidneys the most:
1. Antibiotics, including methicillin, ciprofloxacin, vancomycin, sulfonamides.
2. Analgesics, such as acetaminophen and non-steroidal anti-inflammatory drugs (NSAID): ibuprofen, aspirin, naproxen, and others which people can get only by prescription.
3. COX-2 inhibitors, as celecoxib is (more popular under its brand name Celebrex). Two drugs from this group of medications have been withdrawn from the market due to the fact that they have been proved to be cardiovascular-toxic. These two include valdecoxib (known under the brand name Bextra), and rofecoxib (known under the brand name Vioxx).
4. Heartburn medications of the proton pump inhibitor class. Some of these medications are lansoprasole (known under the brand name Protonix), omeprazole (known as Prilosec), rabeprazol (known under the brand names Aciphex amd Rabcid), esomeprazole (known as Esotrex, Nexium), and pantoprazole (known as Protonix).
5. Antiviral drugs, such as acyclovir (known under the brand name Zovirax) used for treating herpes infections, and indinavir and tenofivir, used for treating HIV.
6. Medication for treating hypertension, such as captopril (also known under its brand name Capoten).
7. Rheumatoid arthritis medications, such as infliximab (more popular under its brand name Remicade); chloroquine and hydroxychloroquine, used for treating malaria and systemic lupus erythematosus, as well as rheumatoid arthritis.
8. Lithium, a drug used for treating bipolar disorder.
9. Anticonvulsants, such as phenytoin (known under its brand name Dilantin) and trimethadione (known as Tridione), drugs used for treating seizures and other conditions.
10. Chemotherapy drugs, such as pamidronate, interferons, carboplatin, cisplatin, tacrolimus, cyclosporine, mitomyciin C, quinine, bevacizumab; as well as some anti-thyroid drugs, such as propylthiouracil, used for treating overactive thyroid.
What should you do instead?
- Do not take any medicine, drug or substance unless you are under a healthcare provider’s supervision.
- Do not take pills or substances given to you by a stranger or even a friend.
- If you do take a medication or other substance and feel ill, contact your healthcare provider immediately.
- If you need to have an imaging test or colonoscopy, let your healthcare provider know if you have kidney disease or are at risk for getting it.
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